Toksisitas Fraksi Sari n-Heksan Daun Kopasanda (Chromolaena odorata (L.) R.M King & H.Rob) terhadap Larva Udang dengan Metode BSLT (Brine Shrmp Lethality Test)

Ayu Yolanda Ginting (Program Studi Farmasi, Sekolah Tinggi Ilmu Kesehatan Indah, Medan, Indonesia)
Sumardi Sumardi (Fakultas Farmasi, Universitas Tjut Nyak Dhien, Medan, Indonesia)
Vierza Mierza (Fakultas Farmasi, Universitas Tjut Nyak Dhien, Medan, Indonesia)

Jurnal Indah Sains dan Klinis
Vol. 1 No. 1 (2020)

Kopasanda leaf plants (Chromolaena odorata (L.) R.M.King & H.Rob) are plants commonly used as medicinal ingredients empirically. The people of East Aceh use it as a wound medicine. Preliminary tests show that the extract and its partitions have a toxic effect on shrimp larvae. In this study, the soluble extract of n-hexane was fractionated using column chromatography with isocratic mobile phase n-hexane: ethyl acetate (7: 3) and silica gel stationary phase. Analysis of the chemical content profile using thin layer chromatography showed that there were polyphenol organic compounds. The fraction 7 obtained shows that it is toxic to shrimp larvae of Artemia salina Leach.