Vierza Mierza
Fakultas Farmasi, Universitas Tjut Nyak Dhien, Medan, Indonesia

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Toksisitas Fraksi Sari n-Heksan Daun Kopasanda (Chromolaena odorata (L.) R.M King & H.Rob) terhadap Larva Udang dengan Metode BSLT (Brine Shrmp Lethality Test) Ayu Yolanda Ginting; Sumardi Sumardi; Vierza Mierza
Journal of Indah Science and Clinic Vol. 1 No. 1 (2020)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v1i1.5

Abstract

Kopasanda leaf plants (Chromolaena odorata (L.) R.M.King & H.Rob) are plants commonly used as medicinal ingredients empirically. The people of East Aceh use it as a wound medicine. Preliminary tests show that the extract and its partitions have a toxic effect on shrimp larvae. In this study, the soluble extract of n-hexane was fractionated using column chromatography with isocratic mobile phase n-hexane: ethyl acetate (7: 3) and silica gel stationary phase. Analysis of the chemical content profile using thin layer chromatography showed that there were polyphenol organic compounds. The fraction 7 obtained shows that it is toxic to shrimp larvae of Artemia salina Leach.