Anti-Acne Activity From Biocellulose Mask Formula Containing (Aloe Vera (L.) Burm.F) Essence Combined With Vitamin E

Raissa Fitri (Universitas Sumatera Utara)
Julia Reveny (Department of Pharmaceutical Technology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia)
Urip Harahap (Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, 20155, Indonesia)
Hariyadi Dharmawan (Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia)
Nasri (Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia)

Indonesian Journal of Pharmaceutical and Clinical Research
Vol. 4 No. 1 (2021): Indonesian Journal of Pharmaceutical and Clinical Research

Abstract. Biocellulose mask sheet is a new found pharmaceutical cosmetic design that widely commercial. Mostly due to it’s biodegradable properties, provide an eco-friendly waste. Combination of Aloe vera essence (AE) and Vit E to provide and determine it’s respective anti-acne properties in biocellulose mask form. Formulation of biocellulose mask with the help of Acetobacter xylinum bacteria varied with different formulae: F1 (Vitamin E 1%), F2 (E 2.5 %), F3 (AE 5%), F4 (AE 2.5%+Vit E 1%) and F5 (AE 5%+Vit E 1%) followed antimicrobials test with common acne bacteria by diffusion disk against Propionibacterium acne (PAC) ATCC 6919 and Pseudomonas aeruginosa (PAA) ATCC 27853. Study revealed that each formulae design F1; F2; F3; F4; F5 tested against PAC diffusion disk resulted 7.86; 11.67; 10.13; 112.10; 10.33 mm respectively. As for PAA diffusion disk resulted 7.76; 11.63; 10.33; 11.67; 11.00 mm respectively. Biocellulose mask containing combination of AE 2.5% and Vit E (F4) would provide the best anti-acne activity amongst other formulae.