Effect of Ethanol Extracts of Musa paradisiaca Fruit Pulp and Peels on Haematological Indices and Liver Enzymes of Experimental Rats

Emuesiri Goodies Moke (Department of Pharmacology and Therapeutics, Delta State University, Abraka)
Emuesiri Kohworho Umukoro (Department of Pharmacology and Therapeutics, Delta State University, Abraka)
Evelyn Tarela Ojugbeli (Department of Medical Biochemistry, Delta State University, Abraka)
Theresa Ezedom (Department of Medical Biochemistry, Delta State University, Abraka)
Tarela Melish Elias Daubry (Department of Physiology, Delta State University, Abraka)
Iziegbe Lisa Omorodion (Department of Pharmacology and Therapeutics, Delta State University, Abraka)

Biology, Medicine, & Natural Product Chemistry
Vol 10, No 1 (2021)

Medicinal plants usage in traditional medicine has risen over the years. Musa paradisiaca has been reported that it possesses various therapeutic efficacies. This study is aimed at evaluating the effect of parts of the ethanol fruit extracts of Musa paradisiaca on haematological indices and serum liver enzymes. Thirty Wistar rats were grouped into five groups of six animals each which were administered 200 mg/kg and 400 mg/kg of Musa paradisiac fruit (MPF) pulp extract or peel extract. Haematological indices and liver enzymes were assayed for at the end of the 14-days experimental period. MPF pulp and MPF peel at 400 mg/kg showed a significant (P<0.05) increase in red cell count and haematocrit level as compared to the control. There was a non-significant (P>0.05) increase in haemoglobin concentration in the treated rats as compared to the control. There was also a non-significant (P>0.05) change in AST, ALT, and ALP level of the treated rats as compared to the control. Fruit pulp and peel of Musa paradisiaca improve erythrocytes count and haematocrit level, and they may not be associated with liver toxicity.