Indian Journal of Forensic Medicine & Toxicology
Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology

The Correlation Study between Some Biochemical Parameters of 256 Covid-19 Cases Considering Diabetes

Ahmed Ab. Jabbar (Unknown)



Article Info

Publish Date
16 Aug 2021

Abstract

Background: Diabetic Mellitus is an independent risk factor in patients with coronavirus disease 2019(COVID-19), but data on the association of diabetes, acute kidney injury, and COVID-19 severityare limitedto Middle East populations.Materials and Methods: This cohort study aimed to investigate these associations in 256 patientssequentially admitted between June 2020 and November 2020, at Emirati Hospital/Erbil. The investigationincluded some main biochemical parameters including liver and kidney function tests. Data analysis wasprocessed by SPSS and the Pearson correlation pathway using log-converted data.Results: Diabetic patients showed the highest correlations between measured parameters, of which glucoselevel showed a positive correlation coefficient (0.13**) with C-reactive protein and other biochemicalparameters. Based on the glycemic status, COVID-19 patients were found in 3 groups, euglycemia groupwith an abundance of 148 (57.81%),hyperglycemiapatients were 67 (26.17%), and 41 of them were diabetics(16.01 %).The Diabetic group showed a significantly (0.0002) increased level of C-reactive Protein and Glucose incomparison with hyperglycemia [CRP 15.38 mg/dl vs 10.09mg/dl, glucose 429.75 mg/dl vs 160.62mg/dl] with a Significantly (0.00374) higher mortality rate (29.26%) than that (10.44%), and (6.75%) ofhyperglycemia, and euglycemia, respectively.Conclusion: Male COVID-19 cases showed higher correlations between the estimated parameters thanfemale cases. Diabetes was significantly associated with elevation of almost all kidney and liver functionparameters. Finally, diabetes followed by COVID-19 disease was related to severe complications and highermortality rates than nondiabetic COVID-19 cases.

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