Indian Journal of Forensic Medicine & Toxicology
Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology

Review of Fungal Infection in Human Beings and Role of COVID-19 Pandemic

Batool Mutar Mahdi (Unknown)



Article Info

Publish Date
16 Aug 2021

Abstract

Background: Fungal infections are common throughout the world. In humans, fungal infections occurwhen an invading fungus takes over an area of the body and the immune system is unable to handle it anderadicate it. Fungi can live in the air, soil, water, and plants and there are also some fungi that live naturallyin the human body.Aim of the Study: To search and review the current literature surrounding fungal infection in different partsof body and role of fungal infection during COVID-19 pandemic.Methods: Henari, MEDLINE, EMBASE, PubMed, and Web of Science were searched using searchcriteria relating to fungal infection and relation with COVID-19 infection. Articles presenting clinical datafor patients with fungal infection and coronavirus infection reported in English only were included. Datadescribing prognosis and outcomes were extracted.Results: 1100 abstracts were identified. Five full texts reporting fungal infection were included. Analysisshowed wide use of empirical broad-spectrum antibacterials drugs in spite of evidence for bacterialcoinfection.Conclusions: Despite frequent prescription of broad-spectrum empirical antibiotics in patients withcoronavirus-associated respiratory tract infections, there is a small number of data to support the associationwith respiratory fungal coinfection. Generation of prospective confirmation to support development ofantimicrobial antibiotics strategy and suitable stewardship specific for the COVID-19 pandemic is urgentlyrequired.

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