JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Vol 11, No 3

Antidiabetic Regimen and Factors Associated with Glycemic Control in Patients with Type 2 Diabetes mellitus in Public Health Centers in Jakarta: A Cross-Sectional Study

Nora Wulandari (Faculty of Pharmacy and Science Universitas Muhammadiyah Prof. DR. HAMKA)
Maifitrianti Maifitrianti (Faculty of Pharmacy and Science Universitas Muhammadiyah Prof. DR. HAMKA)
Fadilla Muthi’ah (Faculty of Pharmacy and Science Universitas Muhammadiyah Prof. DR. HAMKA)
Nava Nur Disya (Faculty of Pharmacy and Science Universitas Muhammadiyah Prof. DR. HAMKA)



Article Info

Publish Date
30 Sep 2021

Abstract

Background:The glycemic control of diabetes mellitus patients is affected by many factors, including its antidiabetic regimen. Objectives: This study aimed to describe the antidiabetic regimen used in patients with T2DM in the public health centres in Jakarta and to evaluate the association of the regimens and other factors with glycemic control. Methods:This was a cross-sectional study conducted in thirteen public health centres in Jakarta with HbA1C of ≤ 7% indicating good glycemic control and > 7% poor glycemic control. The univariate analysis tests were used to analyze factors that potentially associate with glycemic control. Association between antidiabetic regimen and glycemic control were done by Pearson chi-square test and Fisher exact test.Results:Combination of sulfonylureas and biguanides was the most frequent antidiabetic regimen prescribed to the patients. Univariate analysis showed that age, duration of T2DM, route of administration, number of antidiabetics, and number of other daily regular drugs significantly (P<0.05) related to glycemic control.Sulfonylurea and biguanides as monotherapy were significantly (P<0.05) associated with good glycemic control. Conclusion:Sulfonylurea and biguanide as monotherapy were found to be associated with good glycemic control. In contrast, the combination of and with the two did not show the same.

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Journal Info

Abbrev

jmpf

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

JMPF is the first open access journal in Indonesia specialized in both research of pharmaceutical management and pharmacy practice. Articles submitted in JMPF are peer reviewed, we accept review articles and original research articles with no submission/publication fees. JMPF receives manuscripts ...