α-Glucosidase Inhibitor Activity of some Indonesian Syzygium Extracts

Emma J. Pongoh (Jurusan Kimia Universitas Negeri Manado)
Rymond J Rumampuk (Jurusan Kimia Universitas Negeri Manado)
Astin Lukum (Department of Chemistry Universitas Negeri Gorontalo, Bone Bolango, Gorontalo, Indonesia, 96554)
Ardi Kapahang (Jurusan Kimia Universitas Negeri Manado)

Jambura Journal of Chemistry
Vol 3, No 2 (2021): August

The leaves and fruits of Indonesian Syzygium spp such as white pakoba, red pakoba and bombongan have been extracted by ethanol. The ethanolic extract was partitioned with polar solvent gradient using n-hexane, ethyl acetate and n-butanol repeatedly. Each fraction was tested for antidiabetic activity and exhibited varying degrees of antidiabetic activity when tested with α-glucosidase method. Antidiabetic test indicated that the ethyl acetate and butanol fractions of the leaves of pakoba white, red pakoba and bombongan has potential as a source of active compounds.