<![CDATA[Teaching materials that support practicum activities are practical guides. The result of observation at SMPN 1 Brondong shows that the practicum guide used has deficiencies in terms of component completeness. This study aims to: 1) produce qualified practical intructions water pollution based on guided inquiry (valid, practical and effective); 2) to describe the validity, practicality and effectiveness of guided inquiry guide. This research is a development research using Four-D development model, however, in this research and development, activities are carried out only until the development stage. The results of research and development show: 1) produce qualified practical intructions water pollution based on guided inquiry developed based on guided inquiry activity; 2) the validity test results from the categorized experts of the category "very valid (81%)", the results of practicality test result 93% showed practical instructions used practical, the results of the effectiveness test to get 0.65 results on Gain score, students' learning completeness classic obtained percentage 90% indicate effective practice manual and student responses to categorical guidance is very good with a percentage of 98%.]]>
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