Berkala Penelitian Hayati
Vol 9 No 2 (2004): June 2004

UJI EFEK ANTIINFLAMASI EKSTRAK HERBA SURUHAN (Peperomia pellucida L. KUNTH) PADA TIKUS PUTIH JANTAN

Sumi Wijaya (Fakultas Farmasi Unika Widya Mandala Surabaya)
Monica S.W (Fakultas Farmasi Unika Widya Mandala Surabaya)



Article Info

Publish Date
06 Feb 2012

Abstract

Peperomia pellucida L. Kunth herbs (Herba Suruhan) is one of the alternative for inflamation therapy. In this study, albino rats were devided into seven groups. The first three groups was administered orally the extract of Suruhan herbs 1500 mg/Kg body weight, 2000 mg/Kg body weight and 2500 mg/Kg body weight. The next three groups were given Indomethacine solutions with the doses of 13.5 mg/Kg body weight, 15.8 mg/Kg body weight and 15 mg/Kg body weight, and the last groups (control) were given 1% of PGA suspension alone. Fifty microliter of Carrageen solution of 1.5% was injected subcutaneously to all rats in those group.The volume of the foot paw of albino male rat injected with carrageen, was measured and recorded for 4 hours. The number of leucocyte and the number of differential count were observed every two hour, namely at the fourth, sixth and eight hours following carrageen injection. There were significant differences in the antiinflamation effect using plethysmometer and the number of leucocyte counts between control and all the treatment group. For the differential count, not all the results showed significant differences.

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Journal Info

Abbrev

jurnal

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

Description

Berkala Penelitian Hayati is a half yearly international peer reviewed, an open access life science journal. The journal was published by The East Java Biological Society and formerly used the Indonesian language. The first edition of this journal is Vol 1 No 1 in June 1995. It was accredited by ...