ANTIANEMIA SUPPLEMENTATION COMBINATION WITH VITAMIN C ON HEMOGLOBIN LEVELS AMONG PREGNANT WOMEN IN PRIMARY HEALTH CARE CENTER, JEPARA, INDONESIA

Poppy Diah Palupi (Department of Pharmacology and Clinical Pharmacy, Nusaputera School of Pharmaceutical Science, Semarang, Indonesia)
Mohammed Safwan Ali Khan (Department of Biomedical Sciences, School of Medicine, Nazarbayev University, 5/1 KereiZhanibek Khandar Str.53 Kabanbay Batyr Avenue, Nur-Sultan city, 010000 Kazakhstan)
Kukilo Kenuk Karseno (Department of Pharmacology and Clinical Pharmacy, Nusaputera School of Pharmaceutical Science, Semarang, Indonesia)

Jurnal Farmasi Sains dan Komunitas
Vol 18, No 2 (2021)

Blood volume escalation during pregnancy leads to an increase in iron needs. Pregnant women are prone to maternal anemia that is caused by iron, folic acid, vitamins B2, B12, A, and C deficiency and may serve as causative factors that aggravate anemia. Concerning the problem, this clinical investigation determined the effect of antianemia supplementation and its combination with vitamin C on hemoglobin levels during pregnancy. This study is a quasi-experimental involving 34 patients who consumed antianemia supplements with or without vitamin C. The treatment group was given a combination of antianemia supplement Fe Fumarate 180 mg-Folic Acid 400 mcg and vitamin C 100 mg. The positive-control group was administrated with antianemia supplement Fe Fumarate 180 mg-Folic Acid 400 mcg. After 28 days, blood samples were taken to measure the hemoglobin levels. The hemoglobin levels were found to have a statistically significant difference (p0.05) between that group receiving a combination of antianemia-vitamin C and the other group administered with antianemia alone.