Indonesian Journal of Chemistry
Vol 21, No 6 (2021)

Phytochemistry and Pharmacology of Munronia Genus (Meliaceae)

Kindi Farabi (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang Km. 21, Jatinangor, Sumedang 45363, Indonesia)
Unang Supratman (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang Km. 21, Jatinangor, Sumedang 45363, Indonesia Central Laboratory, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang Km. 21, Jati)



Article Info

Publish Date
23 Aug 2021

Abstract

Munronia is a genus in the Meliaceae family, which consists of over 17 species that are distributed in the subtropical and tropical area of Asia, including southern China, Vietnam, Myanmar, Sri Lanka, India, Indonesia, and the Philippines. It is known that these plants contain valuable bioactive compounds. Since the first isolation of new stigmastane steroid was reported in 2003, researchers have been able to study the chemical composition of these plants, especially the largest secondary metabolite obtained, limonoid. About 97 compounds were isolated successfully and characterized. The reported compounds showed various biological activities, such as antifeedant, antimicrobial, antiangiogenic, cytotoxic against several cancer cell lines, inducing apoptosis, and anti-tobacco mosaic virus activities. Therefore, the results suggest that the use of this plant as a source of bioactive compounds is promising for the medicinal chemistry field.

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Journal Info

Abbrev

ijc

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

Indonesian Journal of Chemistry is an International, peer-reviewed, open access journal that publishes original research articles, review articles, as well as short communication in all areas of chemistry including applied chemistry. The journal is accredited by The Ministry of Research, Technology ...