This study aims to examine whether leverage, ownership structure and board size affect the profitability of a company's financial statements that are included in the LQ-45 partially or simultaneously. In this study using the documentation method in order to collect data where this data is in the form of a company's annual financial report document obtained from the official length of the Indonesian Stock Exchange and then tested using multiple linear regression analysis techniques. The results of the t test show that partially institutional ownership has a positive effect on profitability where the significance is 0.014<0.05, managerial ownership has a negative effect on profitability where the significance is 0.142>0.05, then for board size has a positive effect on profitability, the significance value 0.041<0.05, and leverage has a negative effect on profitability where the significance value is 0.682>0.05. Then for the simultaneous effect of all independent variables have an influence on profitability
                        
                        
                        
                        
                            
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