Proceeding of Mulawarman Pharmaceuticals Conferences
Vol. 13 (2021): Proc. Mul. Pharm. Conf.

Uji Aktivitas Minyak Atsiri Daun Pala (Myristica fragrans Houtt.) Sebagai Antibakteri: Activity Test of Nutmeg Leaf Essential Oil (Myristica fragrans Houtt.) as Antibacterial

Halimathussadiah Halimathussadiah (Laboratorium Penelitian dan Pengembangan Kefarmasian ?Farmaka Tropis? Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia)
Dewi Rahmawati (Laboratorium Penelitian dan Pengembangan Kefarmasian ?Farmaka Tropis? Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia)
Niken Indriyanti (Laboratorium Penelitian dan Pengembangan Kefarmasian ?Farmaka Tropis? Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia)



Article Info

Publish Date
10 Apr 2021

Abstract

Antibacterials are compounds that are useful in controlling bacterial growth that can harm humans and avoid pathogens that can be a source of disease for the body. Nutmeg essential oil (Myristica fragrans Houtt.) Is known to contain various compounds including flavonoids, alkaloids, phenols and terpenoids which can be used as antibacterial agents. The purpose of this study was to determine the activity of nutmeg essential oil as an antibacterial. The antibacterial test method uses the well diffusion method using a 6 mm buffer. Nutmeg essential oil is made in 4 concentration series, namely F1 (40%), F2 (60%), F3 (80%), F4 (100%), 10% DMSO control. The data analysis method is a descriptive method in the form of data that is presented in the form of tables and figures. The results of the antibacterial activity test showed that the essential oil of nutmeg leaves had antibacterial activity against Escherchia coli, Staphylococcus aureus, Vibrio cholerae, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylococcus epidermidis in the best concentrations, namely 100% respectively of 6.79mm ? 0.67; 5.56mm ? 0.18; 6.75mm ? 0.82; 14.61mm ? 1.10; 17.03 mm ? 3.90; 5.39mm ? 0.75; control there is no antibacterial activity. The response of each bacteria was medium-strong and the best concentration was taken from the highest concentration because the higher the essential oil concentration of nutmeg leaves, the greater the bacterial inhibitory activity.

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Journal Info

Abbrev

mpc

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Description

LINGKUP DAN TUJUAN Lingkup naskah mencakup bidang ilmu: Kimia Farmasi Biologi Farmasi Farmakologi Teknologi Farmasi dan Farmasetika Farmasi Klinik dan Komunitas Kedokteran dan Bidang ilmu lain yang terkait Tujuan penerbitan adalah memberikan informasi ilmiah tentang perkembangan ilmu pengetahuan dan ...