Total-to-HDL Cholesterol Ratio and Visceral Adiposity Index Correlation in Type Two Diabetics with or without Ischemic Stroke

Karina Rahma Meidiarti (Medical Profession Program, Faculty of Medicine, Sriwijaya University, Palembang, Indonesia)
Phey Liana (Department of Clinical Pathology, Sriwijaya University – Mohammad Hoesin General Hospital, Palembang, Indonesia)
Swanny Swanny (Department of Physiology, Faculty of Medicine, Sriwijaya University, Palembang, Indonesia)
Tungki Pratama Umar (Medical Profession Program, Faculty of Medicine, Sriwijaya University, Palembang, Indonesia)

Majalah Kedokteran Andalas
Vol 44, No 7 (2021): Online Desember 2021

Objective: The study aims to analyze clinical and laboratory data differences, also the correlation of Visceral Adiposity Index (VAI) with other observed parameters in type 2 diabetics with or without ischemic stroke. Methods: This study was conducted as analytic observational study with cross-sectional design. Clinical data were directly collected from patients, followed by laboratory data collection. There was a comparison (Mann-Whitney or independent T-tests) and correlation analysis (Pearson or Spearman). Results: In the ischemic stroke group, the total-to-HDL cholesterol ratio and VAI were significantly higher (p=0.033 and 0.002, respectively) than the non-ischemic stroke group. The total-to-HDL cholesterol ratio and VAI had a significant correlation (p<0.001). Clinical (WC and VAI) and laboratory data (total cholesterol, triglyceride, LDL-C, and total-to-HDL cholesterol ratio) differ significantly in type 2 diabetics with or without ischemic stroke. Conclusion: In both diabetes groups, with or without ischemic stroke, there was a significant correlation between VAI and the total-to-HDL cholesterol ratio.