Jurnal Kesehatan Andalas
Vol 10, No 3 (2021): Online November 2021

Korelasi Glukosa Kapiler Metode Glucose Dehidrogenase-Nicotinamide Adenine Dinucleotide Dengan Glukosa Serum Metode Heksokinase

Syarifah Tridani Fitria (Pogram Pendidikan Dokter Spesialis I Patologi Klinik, Faculty of Medicine, Universitas Andalas, Padang)
Rismawati Yaswir (Bagian Patologi Klinik dan Kedokteran Laboratorium, Faculty of Medicine, Universitas Andalas, Padang.)
Efrida Efrida (Bagian Patologi Klinik dan Kedokteran Laboratorium, Faculty of Medicine, Universitas Andalas, Padang.)



Article Info

Publish Date
27 Jan 2022

Abstract

Rapid and accurate measurement of capillary glucose level using point-of-care testing (POCT) is needed to maintain the patient’s normoglycemic status in obtaining adequate management. The glucose POCT method should be evaluated to determine analytical performance by comparing with the hexokinase method as a reference method to provide accurate and reliable results. Objectives: To determined the correlation between capillary glucose using glucose dehydrogenase-nicotinamide adenine dinucleotide (GDH-NAD)  and serum glucose hexokinase methods. Methods:  This analytic cross-sectional study on 42 outpatients who underwent fasting blood glucose examination at Dr. M Djamil Padang General Hospital. This study was conducted from February until September 2020. Capillary fasting blood glucose was measured using glucose POCT GDH-NAD method and serum glucose with hexokinase method. The Spearman correlation test was used to analyze data, significant if p<0.05. Results: The subjects were 28 male (66.7%),14 female (33.3%) with mean age and hematocrit level was 56.12±12.97 years and 40.90±2.42%, respectively. The median capillary glucose GDH-NAD method and serum glucose hexokinase method were 100.00 mg/dL each, with a median difference was 3.00 mg/dL. Spearman correlation test showed very strong positive correlation and statistically significant (r=0,961;p=<0,001). Conclusion: Capillary glucose GDH-NAD method had a very strong positive correlation with serum glucose hexokinase method.Keywords:  hexokinase, fasting glucose level, GDH-NAD, glucose POCT

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Journal Info

Abbrev

JKA

Publisher

Subject

Health Professions

Description

Jurnal Kesehatan Andalas merupakan Jurnal yang diterbitkan oleh Fakultas Kedokteran Universitas ...