Indonesian Journal of Cancer Chemoprevention
Vol 2, No 1 (2011)

Antioxidant-Free Radical Scavenging of Some Euphorbiaceae Herbs

Sunarni, Titik ( Faculty of Pharmacy, Setia Budi University)
Leviana, Fransiska ( Faculty of Pharmacy, Setia Budi University)



Article Info

Publish Date
31 Jul 2012

Abstract

In order to screen natural antioxidant, the research about antioxidant of some Euphobiaceae herbs,have been conducted.The air-dried herbs of Euphorbia heterophyllaL,Phyllanthus  acidus  (L.) Skeels, and Phyllanthus  buxifolius  Muell Arg were extracted with metanol.The obtained extract was concentratedand then suspended to producen-hexane, ethyl acetat and aqueous fractions. Free radical scavenger activity against DPPH (1,1diphenyl2pycrylhydrazyl) measured by spectrophotometric method and the IC50 value was determined.The compounds of active fraction had been identified by TLC method. All of theherbs showed activity as DPPH scavenger.Among these herbs,Euphorbia heterophylla L. and Phyllanthus buxifolius Muell, Arg. exhibited a strong free radical scavenging of ethyl acetatfraction with IC50 value 5,883g/ml and 4,643g/ml.The result ofTLC by mobile phase n-buthanol acetic acid water(4:1:5) andacetic acid 15% showed flavonoid compound.

Copyrights © 2011






Journal Info

Abbrev

ijcc

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Indonesian Journal of Cancer Chemoprevention (IJCC) is an open access, peer-reviewed, triannual journal devoted to publishing articles on Cancer Chemoprevention including Experimental and Clinical Pharmacology, especially concerning Anti-Oxidants, Anti-Aging, Anti-Inflammation, Anti-Angiogenesis, ...