Synthesis Octyl p-Methoxycinnamate as Sunblock by Transesterification Reaction with the Starting Material Ethyl p-methoxycinnamate

Suzana, . ( Department of Pharmaceutical Chemistry, Faculty of Pharmacy Universitas Airlangga, Surabaya)
Irawati, Nunuk ( Alumnus of Faculty of Pharmacy, Universitas Airlangga, Surabaya)
Budiati, Tutuk ( Department of Pharmaceutical Chemistry, Faculty of Pharmacy Universitas Airlangga, Surabaya)

Indonesian Journal of Cancer Chemoprevention
Vol 2, No 2 (2011)

Synthesis  octyl  p-methoxycinnamate  substance  as  sunblock,  has  been  done  by transesterification  reaction.  The  starting  material  of  the  reaction  was  ethyl  p-methoxycinnamate  isolated  from  Kaempferia  galanga  L.The  transesterification  reaction  was carried out by reacting  ethyl p-methoxycinnamate with octanol. The product was identified by UV-VIS,Infra Red and Mass Spectroscopy. The result of measurements on erythemic %T at various concentrations demonstrate that octyl p-methoxycinnamate is applicable as a sunblock compound. Key  words  :  octyl  p-methoxycinnamate,  transesterification,  ethyl  p-methoxycinnamate,  sunblock