Jurnal Kesehatan
Vol 15 No 1 (2022): Jurnal Kesehatan

Hubungan Lama Menderita Diabetes Melitus dengan Kadar Prothrombin Time (PT) dan Activated Partial Thromboplastin Time (APTT)

Nikma Nikma (Poltekkes Kemenkes Ternate)



Article Info

Publish Date
22 Mar 2022

Abstract

Background: Hyperglycemia, hyperinsulinemia, and insulin resistance have been observed in various studies as the causes of changes in various components that play an important role in hemostasis. Purpose:This study aims to analyze the relationship between the duration of Type 2 DM and the hemostatic conditions of PT and APTT. Methods: This study belongs to an observational study with a cross sectional approach using plasma blood samples that have been filled with the anticoagulant Na citrate 3.2% taken from patients who have met the research sample criteria. The number of samples was 30, all of whom were patients with type 2 diabetes mellitus. Results: Between the duration of DM and PT, the results were not significant (p > 0.05), the PT results here described the extrinsic pathway of blood clotting. Meanwhile, between the duration of DM and APTT, the test results obtained a significant relationship (p < 0.05), this illustrates that there is a significant effect on the intrinsic pathway with the duration of DM

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Journal Info

Abbrev

juke

Publisher

Subject

Environmental Science Health Professions Nursing Public Health

Description

JUKE : Jurnal Kesehatan Poltekkes Kemenkes Ternate is an national peer-reviewed journal dedicated to interchange for the results of high quality research in all aspect of health Science. The journal publishes state-of-art papers in fundamental theory, experiments and simulation, as well as ...