Jurnal Buana Farma
Vol. 2 No. 1 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi

SKRINING FITOKIMIA DAN UJI AKTIFITAS ANTIBAKTERI EKSTRAK DAUN TELANG (Clitoria ternatea L.) TERHADAP BAKTERI Pseudomonas aeruginosa

Lia Fikayuniar (Unknown)
Ermi Abriyani (Fakultas Farmasi Universitas Buana Perjuangan Karawang)
Sabila Nur Safitri (Fakultas Farmasi Universitas Buana Perjuangan Karawang)
Didi Jayadi Mulya (Fakultas Farmasi Universitas Buana Perjuangan Karawang)



Article Info

Publish Date
31 Mar 2022

Abstract

Telang leaf (Clitoria ternatea L.) is one of the plants that is often used as a traditional medicine by the people of Indonesia to cure infections which is used by attaching it to the sore, wound or swollen part. The purpose of this study was to determine the antibacterial bioactivity of n-hexane, ethyl acetate, and methanol extracts of telang leaf against Pseudomonas aeruginosa bacteria and to determine the content of secondary metabolites in the extracts of n-hexane, ethyl acetate, and methanol qualitatively by phytochemical screening and thin layer chromatography. The method used in this study is the antibacterial method of pitting with a concentration of 40%, 60%, 80%, 100%, phytochemical screening, and thin layer chromatography with specific spot appearance. The best potential antibacterial bioactivity between n-hexane, ethyl acetate, and methanol extract of telang leaf (Clitoria Ternatea L.) against Pseudomonas aeruginosa is the methanol extract of telang leaf (60%) which has an inhibition zone of 18.57 mm, strong category and based on supporting data. qualitatively by phytochemical screening containing secondary metabolites, namely flavonoids, saponins, tannins, quinones, polyphenols and triterpenoids/steroids as well as TLC results with the appearance of specific Liebermen burchard (LB) spots that are positive blue-black in color, suspected as an antibacterial of the triterpenoid/steroid secondary metabolite group.

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Journal Info

Abbrev

buanafarma

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

Description

The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical ...