Nusantara Medical Science Journal
Volume 7 Issue 1, January - June 2022

MIC and MBC Levels of Combination Camellia Sinensis and Mentha Piperita Extract Mouthwash Against Streptococcus Mutans

Yuani Setiawati (Department of Pharmacology, Faculty of Medicine, Universitas Airlangga)
Muflikhah Ramadhani (a:1:{s:5:"en_US"
s:59:"Medical program, Faculty of medicine, Universitas Airlangga"
})

Jihan Bobsaid (Pharmacy program, Faculty of pharmacy, Universitas Airlangga)
Dennia Oktavia Zahidah Hulwah (Medical program, Faculty of medicine, Universitas Airlangga)



Article Info

Publish Date
16 Apr 2022

Abstract

Introduction: Awareness of Indonesian people in maintaining dental and oral health is low, proved by an increase in the percentage of dental and oral health problems by 2.7%. Caries is a dental and oral health problem that occurs in many children. The main cause of dental caries is Streptococcus mutans. To solve this problem, it is necessary to use herbal mouthwash made from a combination of Camellia sinensis and Mentha piperita extract as an antibacterial against Streptococcus mutans. Methods:  Mouthwash is made through several processes namely plant determination, extraction, and mouthwash making. Minimal Inhibitory Concentration (MIC) is determined by diluted methods, Minimal Bactericidal Concentration (MBC) is determined by the agar streaking method, and colony tests are calculated using colony counters. Results: The result of plant determination showed the plants in this study were Camellia sinensis and Mentha piperita. At a concentration of 6.25%, no growth of bacteria in each repetition with the number of colonies 0 CFU / ml. While at a concentration of 3.125% found the average number of colonies 13 CFU / ml. Conclusions: Based on good MIC and MBC results, mouthwash containing Camellia sinensis and Mentha piperita has been shown to kill and inhibit the growth of Streptococcus mutans bacteria

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Journal Info

Abbrev

jmednus

Publisher

Subject

Materials Science & Nanotechnology Neuroscience

Description

Nusantara Medical Science Journal (NMSJ) is an open access, peer-reviewed journal published by Faculty of Medicine, Hasanuddin University twice a year in June and December. NMSJ encompasses all basic and molecular aspects of medical sciences, with an emphasis on the molecular studies of biomedical ...