The purpose of this study is to find out the feasibility and effectiveness of Tour in Cell interactive media to improve the cognitive skills of high school/MA students. This research uses Research and Development methods consisting of needs analysis, data collection, product design, media validation and design by experts, design revisions, small-scale product trials, product revisions, and wide-scale product trials. Product design in the form of Interactive Media Tour in Cell with material validity of 4.33 including category is very feasible 86.67% and media display validity of 4.13 including category is very feasible with a percentage of 82.72%. At the wide-scale trial stage, the improvement in student learning outcomes with the N-gain test resulted in an average N-gain score of 0.59 with moderate criteria. Based on the results of the study can be concluded that the media Tour in Cell developed is worth using.
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