Artemisia dracunculus L. (tarragon) is a rich source of herbal remedies with antioxidant and anti-inflammatoryproperties. In the present study, the proliferation of bone marrow and spleen cells of mice was evaluated afterextraction of Artemisia dracunculus with 80% of ethanol. Two doses of the extract (500mg/kg body weightand 1000mg/kg body weight) were given to the mice for seven successive days. On day eight, mice weresacrificed and cells from bone marrow and spleen were collected; mitotic index was calculated and resultswere compared with that of methotrexate at a dose 20mg/kg body weight ( positive control ) and distilledwater ( negative control). The results showed that the dose 500mg/kg body weight of Artemisia dracunculusextract caused significant increase in mitotic index in both bone marrow and spleen cells of mice whencompared with negative control. While, the dose 1000mg/kg body weight of Artemisia dracunculus extractcaused significant decrease in mitotic index in both bone marrow and spleen cells of mice when comparedwith negative control.
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