Indian Journal of Forensic Medicine & Toxicology
Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology

Platelet Rich Fibrin( PRF )-A Novel Generation of Regeneration in Endodontics: A Review

Manali Nath (Unknown)
Shashirekha Govind (Unknown)
Siba Prasad Jena (Unknown)



Article Info

Publish Date
24 Mar 2021

Abstract

In the field of regenerative medicine, PRP/PRF whichwas will be is used as a surgical adjuvant becamethe new glorified approach. For the Regenerative endodontic treatment based on the tissue engineeringconcept, creating a favourable environment free of pathogens, for preservation and migration of stem cells,pathogen eradication, stem cell preservation, presence of scaffold facilitating spatial orientation and signalmolecules released by cells is of utmost importance. In tooth revascularisation and revitalization, successfulapplication of platelet concentrates as scaffolds have been reported. Being autologous, comprising of highgrowth factor concentrates and relatively hassle-free preparation in dental setup, platelet concentrates arepreferred. The advancement in the regenerative endodontics field, with the introduction of the differentgeneration of platelet concentrates, is a breakthrough.

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