Indian Journal of Forensic Medicine & Toxicology
Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology

Evaluation of Serum Level of Cystatin C and Fetuin A in Patients with Chronic Renal Failure

Marwa Nabeel Hameed (Unknown)
Khudhair A. Khudhair (Unknown)
Yasir I. abbas (Unknown)



Article Info

Publish Date
17 May 2021

Abstract

The study found that, serum fetuin-A was significantly reduced in CKD patients before dialysis (19.07±4.24 ng/ml) as compared with healthy individuals (22.5±5.94 ng/ml), P<0.01 and in CKD patients after dialysis (19.74±4.25 ng/ml) as compared with healthy individuals. The study found that, serum cystatin C was significantly reduced in CKD patients before dialysis (12.95±1.54 ng/ml) as compared with healthy individuals (8.16±2.37 ng/ml), P<0.01 and in CKD patients after dialysis (12.39±1.66 ng/ml) as compared with healthy individuals. The study showed a significant negative correlation between CKD patients before dialysis and after dialysis regarding cystatine C (r: -0.37). The study found that, blood urea was significantly increased in CKD patients before dialysis (164.3±30.1 mg/dl) as compared with healthy individuals (24.9±3.7 mg/dl), P<0.01 and in CKD patients after (76.1±29.2 mg/dl) as compared with healthy individuals and there was a significant difference in B. urea between CKD patients before and after dialysis (P<0.01). The study also indicated that S. creatinine was significantly increased in CKD patients before dialysis (5.61±1.99 mg/dl) followed by patients after dialysis (3.43±1.47 mg/dl) as compared with healthy individuals (0.57±0.24 mg/dl) (P<0.01). The study showed a significant negative correlation between of Fetuin-A level with B. urea, S. creatinine and S. cysteine in CKD patients before dialysis and after dialysis

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