Microbiology Indonesia
Vol. 4 No. 1 (2010): April 2010

Amantadine Resistant of Indonesian H5N1 Subtype Influenza Viruses During 2003-2008

NI LUH PUTU INDI DHARMAYANTI (Unknown)
FERA IBRAHIM (Unknown)
AMIN SOEBANDRIO (Unknown)

Article Info

Publish Date
03 May 2010

Abstract

The M2 protein of 146 avian influenza (AI) viruses data available in public database (NCBI), including 20 AI isolates used in this study, were sequenced at the M2 protein to find out the probability of mutation and the increase of resistance to amantadine after more than 5 years of their circulation in Indonesia. The results showed that during 2003-2008, around 62.58% (92/147) AI viruses in Indonesia have showed resistance to amantadine and 10 of them have dual mutations at V27A and S31N.

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Journal Info
Microbiology Indonesia
Website

Abbrev

mionline

Publisher

Perhimpunan Mikrobiologi Indonesia

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology

Description

Microbiology Indonesia provides a unique venue for publishing original researches in microbiology (espesially from Indonesian reseachers), and ensures that authors could reach the widest possible audience. Microbiology Indonesia publishes a wide range of research disciplines on bacteria, archaea, ...