Analisis Senyawa Paracetamol (Acetaminophen) dalam Sampel Urin Menggunakan Metode Kromatografi dan Spektrometri

Dianti Pratiwi (Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia)
Dila Qhoirul Nisa (Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia)
Elsya Martia (Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia)
Ivan Iduljana (Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia)
Nurma Dwi Rahmawati (Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia)
Sridevi Anggraini (Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia)

Jurnal Health Sains
Vol. 3 No. 4 (2022): Jurnal Health Sains

Paracetamol (acetaminophen) is a drug that has an analgesic-antipyretic effect. Research has been carried out with the aim of analyzing the compound paracetamol (acetaminophen) in urine qualitatively using Gas Chrotography-Mass Spectrometry (CG-MS) and LC-MS (Liquid Chromathography – Mass Spectrometry). Urine samples were obtained from patients taking paracetamol without changing consumption patterns. The results of the research analysis showed that positive results of acetaminophen-TMS were obtained in urine samples from 1 hour to a day after taking paracetamol tablets but negative results were obtained after more than 1 day of taking tablets.