Evaluasi Konsentrasi Karboksimetilselulosa-Alginat Formula Pasta Gigi Antiseptik Ekstrak Etanol Daun Seledri (Apium graveolens L.)

Suprianto Suprianto (Sekolah Tinggi Ilmu Kesehatan Indah Medan)
Samran Samran (Fakultas Farmasi, Institut Kesehatan Medistra Lubuk Pakam, Indonesia)
Muhammad Gunawan (Program Studi Farmasi, Sekolah Tinggi Ilmu Kesehatan Indah Medan, Indonesia)
Melati Yulia Kusumastuti (Program Studi Farmasi, Sekolah Tinggi Ilmu Kesehatan Indah Medan, Indonesia)

Jurnal Indah Sains dan Klinis
Vol. 3 No. 1 (2022)

Maceration of Celery leaves using 96% ethanol solvent was used to make the extract. Toothpaste is formulated with carboxymethylcellulose and alginate binders. The active ingredient in the form of ethanol extract of Celery leaves has the potential for antibacterial. This study was to evaluate the concentration of carboxymethylcellulose-alginate in the preparation of antiseptic toothpaste of ethanol extract of Celery leaves. Evaluation of production results consisted of organoleptic, homogeneity, spreadability, foam formation, acidity and viscosity. The higher the concentration of carboxymethylcellulose, the lower the foam and spreadability and the higher the viscosity, while the alginate concentration is the opposite. Carboxymethylcellulose-alginate affects the evaluation parameters of antiseptic toothpaste preparations ethanol extract of Celery leaves