Jurnal Ilmiah Farmasi Akademi Farmasi Jember
2017: Desember - Vol.2 No.2

KARAKTERISASI SENYAWA ANALGETIKA-ANTIINFLAMASI N-(4t-BUTILBENZOIL)-p-AMINOFENOL YANG DISINTISES DENGAN KATALIS ASAM

Hadi Barru Hakam Fajar Siddiq, Dewi Rashati, Farida Suryaningsih (Unknown)



Article Info

Publish Date
28 Jan 2021

Abstract

The N-(4t-Butylbenzoyl)-p-Aminophenol compound was a synthesis compound between p-aminophenol and 4t-Butylbenzoyl chloride by using H2SO4 catalyst. The addition of H2SO4 catalyst purposed to accelerate the rate of rection in the synthesis of the compound and increased yield of product. The N-(4t-Butylbenzoil)-p-Aminophenol compound is beneficial as an antiinflammatory analgesic. This research were proposed to determine characteristics of the anti-inflammatory analgesic synthesis of N-(4t-Butylbenzoyl)-p-Aminophenol compound by using H2SO4 catalyst. Characterization conducted in this research were physical and chemical characterization. The physical characterization were organoleptic test, crystal form test and melting point test. While chemical characterization were UV-Vis spectrophotometry and FTIR. Result of organoleptic test showed sample had powder form, white-gray colour and not taste. Melting point of N-(4t-Butylbenzoyl)-p-Aminophenol compound was 193.33 °C. The optimum wavelength of UV-Vis spectrophotometry got 2 peaks at the wavelengths 290 and 295 nm. The result of FTIR showed that N-(4t-Butylbenzoyl)-p-Aminophenol compound had peaks.Keywords: N-(4t-butyl benzoil)-p-aminophenol, catalyst

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Journal Info

Abbrev

jurnal_ilmiah_farmasi

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Ilmiah Farmasi Akademi Farmasi Jember merupakan Jurnal yang menampung artikel ilmiah hasil penelitian di seluruh bidang Farmasi, seperti Farmasi Bahan Alam, Kimia Farmasi, Farmasetika, Farmasi Klinis, Farmasi Komunitas, dan bidang farmasi ...