The purpose of this study is to find out the effect of investment, HDI, labor, and inflation on gross regional domestic product (PDRB) in districts/cities incorporated in the Gerbangkertosusila area. Observation data was obtained from BPS East Java Province and East Java Provincial Investment Office with time series 2010-2019. Data analysis methods use multiple linear regressions. The result is known that in all districts / cities free variables consisting of investment, HDI, labor, and inflation together have a positive influence on the bound variable, namely PDRB. Keywords: investment, HDI, labor, inflation, GRD. The investment variables of Mojokerto Regency and Surabaya City have a positive and significant effect on the PDRB. Lamongan Regency investment variables have a negative and significanteffect on the PDRB, investment variables in other districts / cities do not have a significant effecton the PDRB. IPM variables in all districts / cities have a positive and significant effect on PDRB. Lamongan Regency labor variables have a negative and significant effect on PDRB, while labor variables in other districts / cities do not have a significant effect on PDRB. Inflation variables have a significant influence on the PDRB of Surabaya City.
                        
                        
                        
                        
                            
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