Indonesian Journal on Medical Science (IJMS)
Vol 9 No 1 (2022): IJMS 2022

Efek Pemberian Ekstrak Etanol Daun Alpukat (Persea Americana Mill) Terhadap Penyembuhan Luka Bakar Pada Kelinci (Oryctolagus Cunicullus)

Wahyu Tri Pamungkas (Politeknik Kesehatan Bhakti Mulia)
Siwi Hastuti (Politeknik Kesehatan Bhakti Mulia)
Sri Saptuti Wahyuningsih (Politeknik Kesehatan Bhakti Mulia)



Article Info

Publish Date
28 Jan 2022

Abstract

Burns are injuries caused by direct body contact with hot objects or exposed to fire. Burns not only cause skin damage, but can also affect the body's systems. Avocado leaf (Persea americana Mill) is a medicinal plant known to contain compounds that play a role in wound healing, such as flavonoids, saponins, tannins and alkaloids. This study aims to determine the ethanol extract of avocado leaves has an effect on healing burns in rabbits. Avocado leaf extract was prepared by maceration using 70% ethanol as a solvent. The wound healing test in rabbits were divided into 5 treatment groups, namely the positive control group which was given lavertan ointment, the negative control group was given yellow vaseline, and 3 test groups were given ethanol extract of avocado leaves with a concentration of 5%, 10% and 20%. Making burns using a heated iron plate was then given to the rabbit's back for 5 treatments. Rabbits were observed every day for one week with statistical analysis One Way ANOVA test. The ethanol extract of avocado leaves with a concentration of 5% 10% and 20% had the effect of wound healing 5% = (11, 27 ± 0.16)%, 10% = (12.62 ± 0.14)%, and 20% = (19.86 ± 0.14)%, which means that the ethanol extract of avocado leaves has positive results on wound healing in rabbits. Avocado leaf ethanol extract can be used to heal burns in rabbits.

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Journal Info

Abbrev

ijms

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Health Professions Medicine & Pharmacology Nursing Public Health

Description

Indonesian Journal on Medical Science (IJMS) (https://doi.org/10.55181/ijms) terbit pertama Vol. 1 No.1 Januari 2014. Setiap edisi terdiri dari kurang lebih 100 halaman, yang artikelnya disajikan dalam bahasa Indonesia, kecuali judul dan abstrak disertai dengan bahasa inggris. Mekanisme ...