JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
JKKI, Vol 8, No 2, (2017)

Effect of regional variation on the total flavonoid level of ethanol extract of mangosteen (Garcinia mangostana) peels

Any Guntarti (Faculty of Pharmacy, Universitas Ahmad Dahlan)
Juniati Annisa (Faculty of Pharmacy, Universitas Ahmad Dahlan)
Mulki Mughniy (Faculty of Pharmacy, Universitas Ahmad Dahlan)
Fitria Rizqi (Faculty of Pharmacy, Universitas Ahmad Dahlan)



Article Info

Publish Date
15 Jun 2017

Abstract

Background : Currently, traditional medicines have been widely used by the public. One of them is mangosteen peel. Extract of mangosteen peel contains alkaloids, glycosides, steroids, flavonoids, polyphenols, and tannins. In order to ensure the quality of the extract so that its chemical content can be guaranteed, it is necessary to standardize the quality of the extract that consists of specific parameters. Objective : This study aims to determine the specific parameters using Thin-Layer Chromatography (TLC) and total flavonoid level of the ethanol extract of mangosteen peel from Kalimantan, Java, and Sumatra. Methods : This research was an explorative study. Extraction technique used was maceration with 70% ethanol solvent. The tested specific parameters, namely the identity of the extract with TLC and total flavonoid level, were determined afterward using visible spectrophotometry with the AlCl3 reagent. Results: The result of the qualitative test with TLC showed that the extract of mangosteen peel contains flavonoids, terpenoids, and anthraquinones. Total flavonoid level of ethanol extract of mangonsteen peel from Kalimantan, Java, and Sumatra were (0.301 ± 0.009); (0.398 ± 0.015); (0,747 ± 0,010) mg QE/g extract, respectively. Conclusion : Extract of mangosteen peel contains flavonoids, terpenoids, and anthraquinones. Total flavonoid level of ethanol extract of mangonsteen peel from Kalimantan, Java, and Sumatra were (0.301 ± 0.009); (0.398 ± 0.015); (0,747 ± 0,010) mg QE/g of extract, respectively.

Copyrights © 2017






Journal Info

Abbrev

JKKI

Publisher

Subject

Medicine & Pharmacology Public Health

Description

JKKI: Jurnal Kedokteran dan Kesehatan Indonesia is a peer-reviewed journal in the field of medical and health sciences. This journal is designed as a place of dissemination of information and scientific knowledge, which publishes three times a year. It publishes original article, article review, and ...