Online business has increased during the COVID-19 pandemic, but the emergence of a number of problems, namely reduced material supply, price fluctuations because an item is difficult to distribute and slow delivery due to transportation of goods based on the type of transportation used (Trucks, Trains, Airplanes and Ships). a number of declines due to the COVID-19 virus pandemic, resulting in longer order waiting times. Pick-up and Delivery Issues are variations of Vehicle Routing Issues that appear in many real-world transportation scenarios, such as product delivery and courier services. This work studies the Pickup and Delivery Problem with Time Windows, where goods must be transported from one location to another, with taking into account certain time limits and vehicle capacity. This aims to minimize the number of vehicles used, as well as operational costs for all routes. To solve this problem, a mathematical model in the form of is used Mixed Integer Linear Programming (MILP) from Pickup and Delivery Problems with Time Windows
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