International Journal of Health and Pharmaceutical (IJHP)
Vol. 2 No. 1 (2022): February 2022

Antioxidant Activity Test Combination Of Cantigi Leaf Extract (Vaccinium varingiaefolium) And Nail Henna Leaf Extract (Lawsonia inermis Linn)

Mokhamad mahroji (Master of Pharmaceutical Sciences, Faculty of Pharmacy, Pancasila University, Jakarta, Indonesia)
Shelly Taurhesia (Master of Pharmaceutical Sciences, Faculty of Pharmacy, Pancasila University, Jakarta, Indonesia)
Dian Ratih Laksmitawati (Master of Pharmaceutical Sciences, Faculty of Pharmacy, Pancasila University, Jakarta, Indonesia)



Article Info

Publish Date
08 Feb 2022

Abstract

Traditionally, cantigi leaves ( Vaccinium varingiaefolium ) are used to heal wounds,swelling, burning, pain, ulcers, and function as analgesic, anti-inflammatory and antiinflammatory. inflammation, and treat fine wrinkles . henna leaves ( Lawsonia inermisLinn ) which contains glycosides, steroids, phytosterols, saponins, tannins, andflavonoids which are reported to have benefits for treating boils, scabies, headaches,back pain, and can accelerate hair growth . Cantigi leaves and fruit are reported tocontain anthocyanin compounds that function as antioxidants . while the antioxidantscontained in cantigi leaves are Beta.-mono-olein , Hexadecanoic acid, and methyl ester. The flavonoids contained in henna leaves also have the potential as antioxidants. Weare often exposed to oxidation both produced from within the body or from outside suchas pollution, cigarette smoke, UV radiation and food. Antioxidants will neutralize thesefree radicals so they do not have the ability to steal electrons from cells and DNA.Cantigi leaves and henna leaves were macerated by kinetic maceration method with70% ethanol as solvent. Antioxidants were measured using the DPPH method, thesingle extract of cantigi gave an IC 50 value of 119.23 ± 4.41 µg/mL , while the extractof a single nail henna gave an IC 50 value of 38.38 ± µg/mL. The combination ofcantigi leaf extract and nail henna leaf extract with a ratio of 1:1; 2:1 and 1:2 gavevery strong IC50 values, namely 33.84 µg/mL; 40.40 µg/mL and 29.85 µg/mL,respectively. It was concluded that the combination of cantigi leaf extract and nailhenna leaf extract with a ratio of 1:2 gave the best IC50 value of 29.85 µg/mL.

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Journal Info

Abbrev

IJHP

Publisher

Subject

Nursing Public Health

Description

International Journal of Health and Pharmaceutical (IJHP) e- ISSN : 2808-845X is a communication media and scientific publication in the health and pharmaceutical fields published by Inara Publisher. International Journal of Health and Pharmaceutical (IJHP) contains articles from research focusing ...