<![CDATA[ABSTRACT Sodium Carboxymethyl Cellulose (CMC Na) commonly used as binder on toothpaste becauseits has good viscosity. The active ingredient of two type of toothpaste is ethanol extract of guava leaves (EEDJB) and ethanol extract of red betel leaf (EEDSM), respectively which has the potential for antiplaque on teeth. The purpose of this study to determine the effect of variations concentration of CMC Naagainst physical characteristics from toothpaste EEDJB and EEDSM. EEDJB and EEDSM had made by maceration method using ethanol 70% as a solvent. Three different concentrations of CMC Naof toothpaste formulation EEDJB are FI (0.5%); FII (0.75%); FIII (1.00%) and EEDSM are FI (0.45%); FII (0.67%); FIII (0.90%). Toothpaste of EEDSM and EEDJB had tested against its physical characteristics. Based on theexperimental results of toothpaste formulations EEDJB and EEDSM states that the higher concentration of CMC Na hadn’t affect the organoleptic and foaming test, but the viscosity becomes higher and the potency dispersive of becomes decreases. Value of viscosity (dPas) toothpaste EEDJB for FI (123,33 ± 5,77); FII (256,67 ± 20,81); FIII (283,33 ± 10,40), while toothpaste EEDSM for FI (125±5); FII (250±25); FIII (316,6± 28,87. The average of the potency dispersive (cm2) of toothpaste EEDJB with a load of 150 grams for F1 (1,75); F2 (1,21); F3 (0,89), while toothpaste EEDSM with a load of 150 grams for F1 (1,64); F2 (1,26); F3 (0,73). Keywords : CMC Na, ethanolic extract of guajava leaves, ethanolic extract of red betle leaves, toothpaste]]>
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