Makara Journal of Science
Vol. 19, No. 1

Flavonoid Compounds from the Bark of Aglaia eximia (Meliaceae)

Sianturi, Julinton (Unknown)
Purnamasari, Mayshah (Unknown)
Mayanti, Tri (Unknown)
Harneti, Desi (Unknown)
Supratman, Unang (Unknown)
Awang, Khalijah (Unknown)
Hayashi, Hideo (Unknown)



Article Info

Publish Date
20 Mar 2015

Abstract

Three flavonoid compounds, kaempferol (1), kaempferol-3-O-α-L-rhamnoside (2), and kaempferol-3-O-β-D-glucosyl-α-L-rhamnoside (3), were isolated from the bark of Aglaia eximia (Meliaceae). The chemical structures of compounds 1–3 were identified with spectroscopic data, including UV, IR, NMR (1H, 13C, DEPT 135°, HMQC, HMBC, 1H-1H-COSY NMR), and MS, as well as a compared with previously reported spectra data. All compounds were evaluated for their cytotoxic effects against P-388 murine leukemia cells. Compounds 1–3 showed cytotoxicity against P-388 murine leukemia cells with IC50 values of 1.22, 42.92, and >100 mg/mL, respectively

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Journal Info

Abbrev

publication:science

Publisher

Subject

Description

Makara Journal of Science publishes original research or theoretical papers, notes, and minireviews on new knowledge and research or research applications on current issues in basic sciences, namely: Material Sciences (including: physics, biology, and chemistry); Biochemistry, Genetics, and ...