Jurnal Farmasi Sains dan Praktis
Vol 8 No 2 (May-August 2022)

EFFECT OF GELATIN AS A BINDER ON TURMERIC EXTRACT TABLET FORMULATION

Adi Permadi (Department of Chemical Engineering, Faculty of Industrial Technology, Universitas Ahmad Dahlan, Yogyakarta 55191, Indonesia)
Iis Wahyuningsih (Department of Pharmacy, Faculty of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta 55166, Indonesia)
Sapto Yuliani (Department of Pharmacy, Faculty of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta 55166, Indonesia)
Ibdal Satar (Department of Food Technology, Faculty of Industrial Technology, Universitas Ahmad Dahlan, Yogyakarta 55191, Indonesia)
Ratna Wijayatri (Departement of Pharmacy, Faculty of Health Science, Universitas Muhammadiyah Magelang, Magelang 56172, Indonesia)



Article Info

Publish Date
30 Jun 2022

Abstract

In line with the progress of the times in which all aspects of many products are made easy and comfortable for the wearer. The main components for tablet formulations are the fillers, binders, crushers, thinners and lubricants. Among these components, the binders play a key role on the powder cohesion properties during the formation of tablet granules. Due to the effect of gelatin on the tablet properties are positive significant, therefore, this work tries to evaluate the effect of gelatin in the different formulation on the turmeric extract tablets. In this study, turmeric extract tablets were formulated using 15 g of turmeric extract, 35 g of aerosil, 12.8 g of lactose, 1% magnesium stearate, 200 ml of aquadest and gelatin as a binder. To evaluate the effect of gelatin on the tablet formulation, the gelatin was then prepared in different formulation namely 0.1 g (formulation A), 0.2 g (formulation B) and 0.5 g (formulation C), respectivley. Based on the tablet properties, the turmeric tablet with formulation C met the standard requirements of friability less than 1%, the hardness in the range of 4 -8 kg and disintegration time under 15 minutes.

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Journal Info

Abbrev

pharmacy

Publisher

Subject

Immunology & microbiology Medicine & Pharmacology Public Health

Description

Jurnal Farmasi Sains dan Praktis aims to serve the updated scientific knowledge for international researchers in pharmaceutical sciences. Jurnal Farmasi Sains dan Praktis (JFSP) publishes review article, original article, as well as short communication in the all scopes of Pharmaceutical Science ...