Pengaruh Ekstrak Jahe Merah (Zingiber Officinale.) Terhadap Pertumbuhan Bakteri Shigella Dysentriae

NI KADEK SINTA DWI CHRISMASYANTI (Fakultas Kedokteran Universitas Udayana)
KADEK DENIK SUASTINI (Fakultas Kedokteran Universitas Udayana)
NI LUH SURAS AMOURA CAWIS (Fakultas Kedokteran Universitas Udayana)
NI WAYAN SUCINDRA DEWI (Departemen Farmakologi dan Terapi Fakultas Kedokteran Universitas Udayana)

Hang Tuah Medical Journal
Vol 18 No 2 (2021): Hang Tuah Medical Journal

Abstract Diarrheal disease in Indonesia is still a high health problem for its morbidity and mortality rates. Diarrhea is still a cause of death in children under 5 years, amounting to 25.2%. Diarrhea morbidity in Indonesia during 2015 reached 6,897,463 and diarrhea that had been handled reached 2,544,084 or as much as 36.9%. The most important and most common cause of diarrhea in developing countries is Shigella, especially Shigella dysentriae and Shigella boydi which causes diarrhea with dysentery. One natural ingredient that has the potential to treat Shigella Dysentriae bacteria is ginger (Zingiber officinale). The ginger plant itself is very abundant in Indonesia. The antibacterial effect against Shigella dysenteriae is due to the active ingredient in ginger, namely gingerol, which inhibits the antibacterial activity of phenolics, flavonoids with an inhibitory mechanism by denaturing bacterial cell wall proteins.