Biomedical Journal of Indonesia
Vol. 7 No. 1 (2021): Vol 7, No 1, 2021

Sarcopenia from Pathophysiology to Clinical : Literature Review

Rachmat Hidayat (Department of Biology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Nur Riviati (Department of Internal Medicine, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)

Article Info

Publish Date
01 Jan 2021

Abstract

The causes of sarcopenia are thought to be multifactorial including: environmental factors, illness, activation of inflammatory pathways, mitochondrial dysfunction, loss of neuromuscular junctions, reduced number of satellite cells and changes in the quality of hormonal function. The mechanism of sarcopenia occurs because the aging process coupled with reduced physical activity can cause the formation of cytokines to increase so that inflammation is easy, insulin resistant, anabolic resistance and neuromuscular impairments.

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Journal Info
Biomedical Journal of Indonesia
Website

Abbrev

bji

Publisher

Universitas Sriwijaya

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Biomedical Journal of Indonesia is an open access, peer-reviewed journal that focus on basic medical sciences, emphasizing on providing the molecular studies of biomedical problems and molecular mechanisms to integrate researches in all aspects of human health. BJI is dedicated to publishing ...