The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Vol 15, No 3 (2014): VOLUME 15, NUMBER 3, December 2014

Fatty Liver and Its Associated Factors among Breast Cancer Patients in Dharmais Cancer Hospital, Jakarta

Philip Waruna (Department of Radiology, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo General National Hospital, Jakarta)
Kardinah - (Department of Radiology, Dharmais Cancer Hospital, Jakarta)
Joedo Prihartono (Department of Community Medicine, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo General National Hospital, Jakarta)
Noorwati Sutandyo (Department of Internal Medicine, Dharmais Cancer Hospital, Jakarta)



Article Info

Publish Date
01 Dec 2014

Abstract

Background: Fatty liver is frequently found during ultrasound (US) examination of breast cancer patients. It is not known how the association between breast cancer and fatty liver. This study was aimed to obtaine the prevalence of fatty liver in breast cancer patients and its association with clinical characteristics of the patients.Method: This was a cross-sectional study in Dharmais Cancer Hospital, Jakarta. Study subjects were breast cancer patients who came between January 2011 and December 2013. Fatty liver was assessed by using abdominal US and were grouped into mild, moderate, and severe. Clinical characteristics of the patients included age, body mass index (BMI), menopausal status, breast tissue density using Breast Imaging Reporting and Data System (BI-RADS), and immunohistochemical estrogen receptor (ER) status.Results: A total of 72 patients were enrolled during the study period with the mean age of 47.5 years. Fatty liver was found in 68 (94.4%) patients. Sixty (83.3%) patients had moderate-to-severe fatty liver. Patients with moderate-to-severe fatty liver had significantly higher BMI (26.9 ± 5.39 vs. 23.6 ± 4.05 kg/m2; p = 0.005). Fatty liver was not associated with the patient’s age, menopausal status, and breast tissue density.Conclusion: This study showed that the prevalence of fatty liver in breast cancer patients is very high. Fatty liver shows significant association with obesity but is not associated with breast tissue density or estrogen receptor status. Keywords: breast cancer, breast cancer density, fatty liver, estrogen receptor

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Journal Info

Abbrev

jghe

Publisher

Subject

Medicine & Pharmacology

Description

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy is an academic journal which has been published since 2000 and owned by 3 Societies: The Indonesian Society of Gastroenterology; Indonesian Association for the Study of the Liver; The Indonesian Society for Digestive ...