Jurnal Penelitian Farmasi dan Herbal
Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL

FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN GEL HAND SANITIZER EKSTRAK ETANOL DAUN BAYAM MERAH (Amaranthus Tricolor L.) TERHADAP BAKTERI Staphylococcus aureus & Eschericia coli

Zola Efa Harnis (Farmasi)



Article Info

Publish Date
31 Oct 2022

Abstract

Red spinach has function as skin antiseptic. It has antibacterial activity because it contains compounds such as tannins, flavonoids, saponins, and steroids. The purpose of formulation and test of antibacterial activity of hand sanitizer gel preparation red spinach extract and evaluation of physical quality of hand sanitizer. Antibacterial activity test was measured by diffusion method using paper disk to measuring the diameter of the bacterial growth inhibition zone of Escherichia coli and Staphylococcus aureus. Concentration extract ethanol of leaf red spinach (and formula of hand sanitizer gel used (F1) blanco; (F2) 5%; (F3) 10%; (F4) 20% and (F5) control positive/detol. Evaluation of physical properties of hand sanitizer gel include of: homogeneity test, stability test and pH test. The results has found showed that antibacterial activity test of gel extract leaves red spinach (on Escherichia coli inhibited at without extract/blanco was 0 mm, concentration of 5% with diameter of inhibit was 14,99 mm, concentration of 10% with diameter of inhibit was 17,26 mm, concentration of 20% with diameter of inhibit was 18,26 mm and using control positive was 19.33. And then for bacteri Staphylococcus aures at concentration of without extract/blanco was 0 mm, 5% with diameter of inhibit was 15,5 mm, concentration of 10% with diameter of inhibit was 15,96 mm and concentration of 20% with diameter of inhibit was 17,43 mm and using control positive was 18.33 mm. So we can conclude that hand sanitizer gel of leaf red spinach have less inhibited growth against Escherichia coli and Staphylococcus aureus.

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Journal Info

Abbrev

JPFH

Publisher

Subject

Medicine & Pharmacology

Description

Aims and Scope The Pharmaceutical & Herb Research Journal is a scientific journal published by Institut Kesehatan Deli Husada which publishes research journals in the field of pharmacy. Indonesia has a lot of natural resources that have the potential to have pharmacological effects. This journal is ...