Jurnal Respirologi Indonesia
Vol 42, No 4 (2022)

Association Between D-Dimer Level with Clinical Severity and Radiological Imaging of Confirmed COVID-19 Patients at RSUP Dr. M. Djamil Padang

Hafis Herdiman (Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Andalas)
Masrul Basyar (Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Andalas)
Oea Khairsyaf (Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Andalas)



Article Info

Publish Date
22 Nov 2022

Abstract

Background: D-dimer could be used as a biomarker to distinguish the severity of COVID-19. High D-Dimer levels are associated with increased clinical severity and poor radiological imaging. This study aims to identify the correlation between D-dimer levels with clinical severity and radiological features of confirmed COVID-19 patients at RSUP dr. M. Djamil Padang.Methods: This was a cross sectional study of 202 COVID-19 confirmed patients at RSUP dr. M. Djamil Padang using medical record data from 1 January to 31 March 2021. The data were collected using convenience sampling technique and analyzed by Kruskal Wallis Test to determine the association between D-dimer levels with clinical severity and radiological features.Results: Majority of patients were in age groups of below 50 and 50-59 years, with equal proportion between men and women, and were in moderate clinical severity (58,4%). Most radiological imaging was in severe degree of 91 patients (45%). The association between D-dimer levels and clinical degree of COVID-19 patients as well as the association between D-dimer levels and severity of radiological imaging of COVID-19 patients were statistically significant (P=0.0001).Conclusion: Elevated D-dimer level was a common feature at COVID-19 confirmed patients. High levels of D-dimer were associated with increased clinical severity and severe radiological features in COVID-19 patients.

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Journal Info

Abbrev

jri

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Jurnal Respirologi Indonesia (JRI) is an online and printed scientific publication of the Indonesian Society of Respirology (ISR). The journal is published thrice-monthly within a year (January, April, July and October). The journal is focused to present original article, article review, and case ...