Radioterapi & Onkologi Indonesia
Vol 13, No 1 (2022): Volume 13 No.1 January 2022

Patients Outcome with Brain Oligometastases Treated with the SIB-IMRT Technique: Dr. Kariadi General Hospital Experience

Christina Hari Nawangsih (Instalasi Radioterapi RS. DR. Kariadi Semarang, Jawa Tengah)
Harman Juniardi (Unknown)
Dion Firli (Unknown)
Sigit Wirawan (Unknown)
Sri Rahayu Subandini (Unknown)
Diaza Okadimar Ariyanto (Unknown)



Article Info

Publish Date
14 Dec 2022

Abstract

Brain metastases are often considered as the end of life in oncologic diseases. Previously, a standalone Whole Brain Radiotherapy (WBRT) had been the standard of care in the case of single or multiple lesions. Currently, Simultaneous Integrated Boost - Intensity Modulated Radiotherapy (SIB-IMRT) permits the delivery of simultaneous doses within a single therapy to the whole brain and the local lesion, therefore shifting the care expectation from palliative towards curative. This study summarizes the outcome in cancer patients with brain oligometastases that were treated with the SIB-IMRT technique. Between April 2020 and April 2021, a total of 29 brain oligometastases patients were treated with the SIB-IMRT technique at Dr. Kariadi General Hospital. Twenty patients completed treatment with a whole-brain dose of 37.5 Gy and tumor dose of 45 Gy, both in 15 fractions. Among fifteen who were successfully followed-up, six at the 6th-month follow-up, complete data of four patients were included. All four patients improved clinically. Evaluation from imaging revealed mass reductions in two patients, while one patient’s metastases were progressing, and the other one showed no changes. Additionally, no patients demonstrated cerebral necrosis as a late side effect.

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Journal Info

Abbrev

JORI

Publisher

Subject

Education Health Professions Medicine & Pharmacology Physics Other

Description

Majalah Radioterapi & Onkologi Radiasi Indonesia (Journal of the Indonesian Radiation Oncology Society) dengan ISSN 2086-9223, satu-satunya majalah dalam bidang Onkologi Radiasi di Indonesia, merupakan majalah di bawah penerbit Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI). Majalah ...