Majalah Obat Tradisional
Vol 27, No 2 (2022)

Standardization of Simplicia Golden Sea Cucumber (Stichopus hermanii) from Pelapis Island, West Kalimantan

Wintari Taurina (Department of Pharmacy, Faculty of Medicine, Tanjungpura University, Pontianak)
Mohamad Andrie (Department of Pharmacy, Faculty of Medicine, Tanjungpura University, Pontianak)



Article Info

Publish Date
31 Aug 2022

Abstract

Standardization of medicinal ingredients and drug preparations is a requirement to ensure reproducibility of pharmaceutical and therapeutic quality. With standardization, it is hoped that it can further increase trust in medicines derived from natural ingredients. Golden sea cucumber is one of the natural ingredients that can be used as raw material for wound healing ointment preparations. The main content in golden sea cucumbers that play a role in wound healing is protein. This study aims to standardize the Simplicia of golden sea cucumber (Stichopus hermanii) originating from Pelapis Island, West Kalimantan. Standardization uses physical, chemical, and microbiological parameters like raw material requirements for standardized herbal medicines (OHT). The test is carried out in the laboratory using the method according to SNI. The results of the Simplicia test of golden sea cucumbers from Pelapis Island, West Kalimantan, included water content of 9.57%, zinc 9.32 mg/kg, cadmium < 0.030 mg/kg, copper < 0.030 mg/kg, lead < 0.066 mg/kg , mercury < 0.007 mg/kg, Total Plate Number 8.0 x 103 colonies/g, E.Coli < 3 APM/gr and Salmonella negative have fulfilled the requirements. The results of the Simplicia test of golden sea cucumbers include 13.4% ash content, 1.52% acid insoluble ash, 36.1% protein, 1.39% total fat, 13.1 mg/kg magnesium, and 10.6 mg iron. /kg. The results of the phytochemical screening of golden sea cucumber Simplicia were positive for containing alkaloids, saponins, and triterpenoids.

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Journal Info

Abbrev

TradMedJ

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

raditional Medicine Journal (Majalah Obat Tradisional), or Trad. Med. J. (ISSN 1410-5918 (print) and ISSN 2406-9086 (online)), is an international scientific journal published by Faculty of Pharmacy, Universitas Gadjah Mada, three times annually. Collaborating with Indonesian Pharmacist Association, ...