JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE
Vol 8, No 2 (2022): OKTOBER 2022

Antiinflamasi Ekstrak Etanol Bunga Kenop (Gomphrena globosa L.) pada Tikus (Rattus novergicus)

Meilina, Rulia (Unknown)
Maghlisa, Ulfa Ibna (Unknown)
Dhirah, Ulfa Husna (Unknown)



Article Info

Publish Date
10 Oct 2022

Abstract

Tujuan dari penelitian ini adalah untuk mengevaluasi potensi aktivitas anti-inflamasi ekstrak etanol dari daun kenop dengan analisis hasil skrining fitokimia. Dua puluh ekor tikus wistar dibagi menjadi 5 kelompok yang terdiri dari 5 hewan. Pengujian anti-inflamasi dilakukan dengan mengukur persentase peradangan pada tikus, setelah pemberian ektrak etanol bunga kenop (40 mg/BB, 80 mg/BB dan 160 mg/BB) sebelumnya diinduksi oleh karagenan. Hasil penelitian menunjukkan ekstrak bunga kenop dosis 160 mg/BB memiliki potensi antiinflamasi sebesar 30% yang mendekati Na-Diklofenak didapatkan persentase rata-rata 38%. Kesimpulan: ektrak etanol bunga kenop ini memiliki aktivitas anti-inflamasi.Kata kunci : Bunga kenop, Na-Diklofenak dan antiinflamasi.The study aimed to evaluate the potential anti-inflammatory activities of ethanol extract of Gomphrena globosa, related to a phytochemical screening analysis. twenty-five Wistar rats were divided into 5 groups of 5 animals. An anti-inflammatory test was carried out by measuring the percentage of inflammation in rats, after the administration of 1 ethanol extract of Gomphrena globosa, which was previously induced by the carrageenan. The doses of extract of Gomphrena globosa160 mg/BB had anti-inflammatory activity compared to 30% is Na-Diclofenac had anti-inflammatory activity compared to 38%. Conclusion: extract of Gomphrena globosa compound had an anti-inflammatory activity.Keywords: Gomphrena globosa L, Na-Diklofenak and anti-inflammatory.

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Journal Info

Abbrev

jhtm

Publisher

Subject

Computer Science & IT Health Professions Medicine & Pharmacology

Description

JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE publishes original research or theoretical papers, notes, and minireviews on new knowledge and research or research applications on current issues in basic sciences (biology, phsycology, pharmacy, midwifery, public health and physics). The journal is ...