FITOFARMAKA: Jurnal Ilmiah Farmasi
Vol 12, No 2 (2022): FITOFARMAKA: Jurnal Ilmiah Farmasi

Formulation and Evaluation of Lime Peel Extract (Citrus aurantiifolia) Gel with Semi-Refined Carrageenan and Glucomannan as Gelling Agent

Shervie Tjitrarukmana (Universitas Sari Mulia)
Siti Malahayati (Unknown)
Liliana Swastina (Unknown)
Kunti Nastiti (Unknown)



Article Info

Publish Date
30 Dec 2022

Abstract

Lime peel extract contains quercetin with sunscreen activity. It could make into gel preparations, which has a transparent semisolid and generally gives a cooling sensation to the skin. A combination of semi-refined carrageenan and glucomannan as a gelling agent can be an alternative to form the strength and elasticity of the gel mass. This study aimed to determine the effect of concentration variations of gelling agents on the physical evaluation of gel preparation results and the optimal formulation for lime peel extract gel as sunscreen. Lime peel extract would make into gel preparation with variations in the concentration of the gelling agent, which are 1%, 1.25%, 1.5%, and 1.75%. Afterward, the physical evaluation included organoleptic, homogeneity, pH, viscosity, spreadability, and adhesion tests. The organoleptic, homogeneity, pH, and adhesion test results show that all formulations meet the requirements. Viscosity test results obtain the best formula III with 3940,00 cPs at 60 rpm . The results of the dispersibility test show the best formulas I and II with 6,10 cm and 5,50 cm. Based on the data analyzed, variations of gelling agents affect the pH, viscosity, spreadability, and adhesion test results. The optimal lime peel extract gel formulation has not defined from the physical evaluation results.

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Journal Info

Abbrev

fitofarmaka

Publisher

Subject

Chemistry Medicine & Pharmacology

Description

FITOFARMAKA mempublikasikan artikel yang berkaitan dengan farmasi, Kimia Farmasi, dan bidang Fitokimia serta akan dipublikasikan secara online. Publikasi secara elektronik akan menambah kekayaan informasi dan pengetahuan ilmiah terutama dari penelitian. Jurnal ini diterbitkan dua kali setahun, ...