FITOFARMAKA: Jurnal Ilmiah Farmasi
Vol 12, No 2 (2022): FITOFARMAKA: Jurnal Ilmiah Farmasi

Antioxidant Activity from Combination of Centella asiatica Herb Extract and Moringa oleifera Leaves Extract

Wahyuni Djoko (Pancasila University)
Shelly Taurhesia (Unknown)
Ratna Djamil (Unknown)



Article Info

Publish Date
30 Dec 2022

Abstract

Antioxidants have an important role in inhibiting free radicals, where free radicals can cause a hereditary disease. Natural medicines that are efficacious as an antioxidant are Gotu kola and kelor leaves. This study aimed to obtain the potential antioxidant compounds in Gotu kola herb extract, kelor leaves extract and the combination using the DPPH method. This research was started by extracting simplicia with 96% ethanol, followed by preparing combination of Gotu kola extract and moringa extract ratio (1:1), (1:2), (1:3), (2:1), (3:1) which was carried out at a concentration of 20, 40, 60, 80, and 100 µl/mL. Furthermore, the antioxidant activity was tested by UV Vis spectrophotometry. Results showed that the IC50 value for the Gotu kola herb extract was 76.66 ± 0.56. Kelor leaves extract 82.66 ± 2.32, a combination of Gotu kola: Moringa (1:1) 74.07 ± 1.16, a combination of Gotu kola: Moringa (1:2) 86.56 ± 1.11, a combination of Gotu kola: Moringa (1:3) 65.09 ± 3.03, a combination of Gotu kola: Moringa (2:1) 56.65 ± 1.61, a combination of Gotu kola: Moringa (3:1) 67.58 ± 2.77. The best potential antioxidant activity was showed in the combination of Gotu kola: Moringa (2:1).

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Journal Info

Abbrev

fitofarmaka

Publisher

Subject

Chemistry Medicine & Pharmacology

Description

FITOFARMAKA mempublikasikan artikel yang berkaitan dengan farmasi, Kimia Farmasi, dan bidang Fitokimia serta akan dipublikasikan secara online. Publikasi secara elektronik akan menambah kekayaan informasi dan pengetahuan ilmiah terutama dari penelitian. Jurnal ini diterbitkan dua kali setahun, ...