Jurnal Kedokteran
Vol 11 No 4 (2022): volume 11 no 4

POTENSI OMEGA-3 BULU BABI (SEA URCHIN) DALAM KONTROL PROGRESIVITAS DEMENSIA ALZHEIMER

Arina Windri Rivarti (University of Mataram)



Article Info

Publish Date
30 Dec 2022

Abstract

With the increasing prevalence of Alzheimer's dementia and the lack of effectiveness of existing drugs in inhibiting the progression of the disease, the investigation of new drug candidates will continue. Omega-3 fatty acids, especially docosahexaenoic acid (DHA), are compounds that can be used as drug candidates for this purpose. Recent scientific evidence, both from epidemiological studies and preclinical trials in experimental animals, shows the potential of these compounds in maintaining cognitive function and inhibiting the progression of Alzheimer's dementia through various mechanisms, including anti-inflammatory, anti-amyloidogenic, and brain neuroplasticity. These compounds are contained in various marine organisms, including sea urchins. Given the wide availability of marine life on the coast and its ability to biosynthesis of omega-3 fatty acids, this marine biota can be considered as the main source of omega-3 in the development of omega-3 as a drug for the protection of cognitive function in Alzheimer's disease dementia.

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Journal Info

Abbrev

jk

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

The Unram Medical Journal managed by the Medical Faculty of Mataram University is a scientific journal to publish the results of the latest research in the field of medical and health related. This journal promote medical sciences generated from basic sciences, clinical, and community research to ...