Pharmacology and Clinical Pharmacy Research
Vol 7, No 3 (2022)

Prebiotic Activity of Pectin from Ambon Lumut Banana (Musa acuminata AAA) Peel

Bertha Rusdi (Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung)
Onoy Rohaeni (Mathematics Department, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung)
Miski A. Khairinisa (Faculty of Pharmacy, Padjadjaran University)
Umi Yuniarni (Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung)



Article Info

Publish Date
12 Jan 2023

Abstract

Banana peel is an agricultural waste that contains pectin. Ambon lumut banana (Musa acuminata AAA) is often consumed in Indonesia, but its peel is rarely utilized thus the availability of Ambon lumut banana peel in Indonesia is high. Pectin selectively increases beneficial gut bacteria, and this is commonly known as prebiotic. This study aims to evaluate the prebiotic activity of Ambon lumut banana peel by observing the growth of a beneficial gut bacteria, Lactobacillus acidophilus, and pathogen enteric bacteria, Escherichia coli, in media (MRSB) enriched with the pectin. The result showed that 1% of Ambon lumut banana peel pectin significantly increased the number of L. acidophilus and decreased the number of E. coli compared to bacteria culture without carbon source (glucose-free MRSB) and bacteria culture with glucose as carbon source. The prebiotic index of Ambon lumut banana peel pectin was 0.53. In addition to that, the short chain fatty acid (SCFA) which is beneficial metabolite of L. acidophilus for human health was also measured using HPLC.  The HPLC analysis results showed that L. acidophilus culture enriched with pectin contains SCFA, including acetic acid, butyric acid, and propionic acid at the concentration of 10.22 µg/mL, 5.38 µg/mL and 0.55 µg/mL respectively.

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Journal Info

Abbrev

pcpr

Publisher

Subject

Medicine & Pharmacology

Description

Pharmacology and Clinical Pharmacy Research (PCPR) is an international, peer-reviewed journal, publishing original research, review, case reports, and commentaries on all aspects of pharmacology and clinical pharmacy. The journal aims to contribute to the scientific committee by publishing the high ...