Bond strength of tissue conditioner (temporary soft denture liner material ) on an acrylic denture base could be affected on the adhesion between these two materials by water solution such as chemical denture cleanser. Cinnamaldehyde contained in cinnamon plant extract (Cinnamomum burmani) is one of the natural agents that can be recommended as a denture cleanser and expected to have a smaller impact on the mechanical properties of material.The aim of this study was to determine the influence of immersion time in plant extract denture cleanser containing cinnamaldehyde on the bond strength of tissue conditioner to acrylic resin. Method: Twenty four rectangular acrylic soft denture liner samples (64 mm x 10 mm x 2,5 mm (ISO 1567:1988)) were divided into 4 groups : group I and II, 1.5 % cinnamon extract immersions (for 7 days and 14 days); group III and IV, aquadest immersions (for 7 days and 14 days). The measurements of samples’s bond strength were done using the Universal Testing Machine on the last day of each group after immersion. The results were submitted to one-way ANOVA and post hoc Bonferroni. Results: There was a significant difference between all groups (p<0.05). The highest average of sample’s bond strength was shown by group III and IV followed by group I and II, respectively. Conclusion: There was effect of immersion time in cinnamon extract denture cleanser on the bond strength of tissue conditioner to acrylic resin
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